Dietology scientists with most funding

Saturday, May 14, 2011

Interesting, a basic search on www.agingportfolio.org with keywords "aging diet" shows over 700 million dollars spent worldwide on related projects. With following trends:

It may actually be more fun to use www.fundingtrends.com for this purpose.

But here is a list of the top investigators in the field and a list of top projects.

Looks like Debas Haile gets the most funding.

Project Funding

Project number	Project title	Investigators	Recipient organization	Funding organization	Year	Funding	Aging Limit ID

N01EY50007-13-0-1	Age-related eye disease study 2 (areds2) coordinating center	CLEMONS TRACI	EMMES CORPORATION	NATIONAL EYE INSTITUTE	2010	$12,237,012	4
1U01CA138962-01	Vitamin d and omega-3 trial (vital)	BURING JULIE E, MANSON ELISABETH	BRIGHAM AND WOMEN'S HOSPITAL	NATIONAL CANCER INSTITUTE	2009	$5,151,147	0
5U01CA138962-02	Vitamin d and omega-3 trial (vital)	BURING JULIE E, MANSON JOANN ELISABETH	BRIGHAM AND WOMEN'S HOSPITAL	NATIONAL CANCER INSTITUTE	2010	$4,819,957	0
N01EY50007-12-0-1	Age-related eye disease study 2 (areds2) coordinating center	CLEMONS TRACI	EMMES CORPORATION	NATIONAL EYE INSTITUTE	2009	$4,677,852	4
1U54HG004969-01	Defining the human microbiome	BIRREN BRUCE W	BROAD INSTITUTE, INC.	NATIONAL HUMAN GENOME RESEARCH INSTITUTE	2009	$4,575,183	0
5U54HG004969-02	Defining the human microbiome	BIRREN BRUCE W	BROAD INSTITUTE, INC	NATIONAL HUMAN GENOME RESEARCH INSTITUTE	2010	$4,135,549	0
EC-1011653	Compliance and effectiveness in hf and chd closed-loop management	ROBINSON, LEON, RAUHUT, KEUR... See more... ROBINSON, LEON, RAUHUT, KEUR, SILVA, LAM, BESTA, VERA, REITER, HEINO, PALOJARVI, BRAMBILLA, MELIS MAYNAR, SUAREZ, PORTOLES PEREZ, BOVER FREIRE, ARRANZ MARCO, LUPRANO, PARKINSON See less...	PHILIPS TECHNOLOGIE GMBH	European Commission	2010	$3,525,000	0
EC-1011653	Compliance and effectiveness in hf and chd closed-loop management	ROBINSON, LEON, RAUHUT, KEUR... See more... ROBINSON, LEON, RAUHUT, KEUR, SILVA, LAM, BESTA, VERA, REITER, HEINO, PALOJARVI, BRAMBILLA, MELIS MAYNAR, SUAREZ, PORTOLES PEREZ, BOVER FREIRE, ARRANZ MARCO, LUPRANO, PARKINSON See less...	PHILIPS TECHNOLOGIE GMBH	European Commission	2009	$3,525,000	0
5M01RR000645-28	General clinical research center	TAPLEY DONALD F	COLUMBIA UNIVERSITY HEALTH SCIENCES	NATIONAL CENTER FOR RESEARCH RESOURCES	1999	$3,414,019	0
5M01RR000645-27	General clinical research center	TAPLEY DONALD F	COLUMBIA UNIVERSITY HEALTH SCIENCES	NATIONAL CENTER FOR RESEARCH RESOURCES	1998	$3,058,448	0
EC-1011653	Compliance and effectiveness in hf and chd closed-loop management	ROBINSON, LEON, RAUHUT, KEUR... See more... ROBINSON, LEON, RAUHUT, KEUR, SILVA, LAM, BESTA, VERA, REITER, HEINO, PALOJARVI, BRAMBILLA, MELIS MAYNAR, SUAREZ, PORTOLES PEREZ, BOVER FREIRE, ARRANZ MARCO, LUPRANO, PARKINSON See less...	PHILIPS TECHNOLOGIE GMBH	European Commission	2008	$2,955,205	0
5M01RR001032-24	General clinical research center	RABKIN MITCHELL T	BETH ISRAEL DEACONESS MEDICAL CENTER	NATIONAL CENTER FOR RESEARCH RESOURCES	1999	$2,832,020	4
5RC2AG036613-02	Can rapamycin retard age-related diseases?	RICHARDSON ARLAN G	UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT	NATIONAL INSTITUTE ON AGING	2010	$2,650,628	0
1RC2AG036613-01	Can rapamycin retard age-related diseases?	RICHARDSON ARLAN G	UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT	NATIONAL INSTITUTE ON AGING	2009	$2,576,662	4
2M01RR001271-16	General clinical research center	DEBAS HAILE T	UNIVERSITY OF CALIFORNIA SAN FRANCISCO	NATIONAL CENTER FOR RESEARCH RESOURCES	1997	$2,365,184	4
3M01RR000079-36S1	General clinical research center	DEBAS HAILE T	UNIVERSITY OF CALIFORNIA SAN FRANCISCO	NATIONAL CENTER FOR RESEARCH RESOURCES	1999	$2,320,154	4
5M01RR000079-36	General clinical research center	DEBAS HAILE T	UNIVERSITY OF CALIFORNIA SAN FRANCISCO	NATIONAL CENTER FOR RESEARCH RESOURCES	1998	$2,316,367	4
5M01RR000645-24	General clinical research center	TAPLEY DONALD F	COLUMBIA UNIVERSITY HEALTH SCIENCES	NATIONAL CENTER FOR RESEARCH RESOURCES	1995	$2,261,540	0
5M01RR000079-35	General clinical research center	DEBAS HAILE T	UNIVERSITY OF CALIFORNIA SAN FRANCISCO	NATIONAL CENTER FOR RESEARCH RESOURCES	1997	$2,201,888	4
5P01AG027211-03	Longevity and stress resistance	VATNER STEPHEN F	UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL	NATIONAL INSTITUTE ON AGING	2009	$2,182,671	4
5M01RR000079-34	General clinical research center	DEBAS HAILE T	UNIVERSITY OF CALIFORNIA SAN FRANCISCO	NATIONAL CENTER FOR RESEARCH RESOURCES	1996	$2,165,418	4
5M01RR001032-23	General clinical research center	RABKIN MITCHELL T	BETH ISRAEL DEACONESS MEDICAL CENTER	NATIONAL CENTER FOR RESEARCH RESOURCES	1998	$2,115,355	4
5P01AG027211-04	Longevity and stress resistance	VATNER STEPHEN F	UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL	NATIONAL INSTITUTE ON AGING	2010	$2,054,477	4
1P01AG031782-01A1	Functional consequences of impaired autophagy in aging	CUERVO ANA M	ALBERT EINSTEIN COL OF MED YESHIVA UNIV	NATIONAL INSTITUTE ON AGING	2009	$2,017,110	0
5U01AG022132-07	Coordinating center for calerie	ROCHON JAMES	DUKE UNIVERSITY	NATIONAL INSTITUTE ON AGING	2008	$2,005,824

Midlife is the best time to start taking suplements

Tuesday, June 1, 2010

Interesting article at LiveScience.com made me actually look at several studies on when it is best to start taking supplements during lifetime (none of them provided conclusive data supporting the hypothesis)

Study: Anti-Aging Supplements Best Taken in Middle Age

To get the most out of so-called anti-aging supplements, it's best to take them during middle age, rather than waiting until after age 65, a new study on rats suggests.

Middle aged rats showed improvements in their physical abilities after receiving anti-aging supplements, while older rats did not, the researchers say.

"It is possible that there is a window during which these compounds will work, and if the intervention is given after that time it won't work," said study scientist Jinze Xu, a postdoctoral researcher at the University of Florida's Institute on Aging.

However, results in rat studies do not necessarily apply to humans, and further research will be needed to confirm the findings.

Rodent strength

Scientists don't fully understand all the processes that lead to loss of function as people age. But more and more research points to the cell's powerhouses, called mitochondria, as an important player in aging. Mitochondria are largely responsible for generating energy within a cell, but they also produce so-called free radicals, which are molecules with extra electrons that can cause damage — throughout the cell and within the mitochondria itself. Too much damage can cause the mitochondria to stop working properly.

To address that problem, many anti-aging studies and supplements are geared toward reducing the effects of free radicals.

The current study tested a commercially available supplement marketed for relieving chronic fatigue and protecting against muscle aging. The supplement contains the antioxidant coenzyme Q10, creatine — a compound that aids in muscle performance — and ginseng, which also has been shown to have antioxidant properties. (Antioxidants ameliorate damage caused by free radicals.)

The researchers fed the supplement to middle-aged 21-month-old and late-middle-aged 29-month-old rats — corresponding to 50- to 65-year-old and 65- to 80-year-old humans, respectively — for six weeks, and measured how strongly their paws could grip. Grip strength in rats is analogous to physical performance in humans, and deterioration in grip strength can provide useful information about muscle weakness or loss seen in older adults.

At the end of the six weeks, grip strength had improved 12 percent in the middle-aged rats compared with controls. No improvement was found in the older group.

Measurements of the function of mitochondria corresponded with the grip strength findings. Stress tests showed that mitochondrial function improved 66 percent compared with controls in middle-aged rats but not in the older ones. That suggests these anti-aging supplements might be of greater effect before major age-related functional and other declines have set in, the researchers said.

More power to the powerhouses

Interestingly, although the older rats had no improvement in physical performance or mitochondrial function, they had less free radical damage compared with the control rats.

The researchers speculate that while the supplement helped to reduce the free radical damage, the damage may have been too great in these old animals for the effect to actually restore the mitochondrial function.

Future research should focus on boosting the health of the mitochondria, the researchers say, since well-working mitochondria will produce fewer free radicals. Also, clinical trials need to be performed to test the effectiveness of the supplements in humans.

The results were published last week in the journal PLoS One. The manufacturers of the supplement donated the quantity used in the study and provided support for the postdoctoral researcher and analyses. The animals used in the study were paid for through grants from the National Institute on Aging.

Aging vs Social Security and Healthcare

Saturday, May 1, 2010

Interesting observation - Google Trends shows that people search four times more for Social Security and Healthcare than for Aging.

Source: Google Trends

From this we can assume that people care less about aging than about Social Security and Healthcare and are highly influenced by public media (see the spike in healthcare around the vote for healthcare reform) then they care about aging.

This needs to be changed. Aging is the Most important issue our society is facing. We need to find ways to slow it down first (Aging Diet) and then to stop it entirely and get back to our regular daily routines.

Aging Diet is Live!

Wednesday, April 21, 2010

Here we will discuss various natural foods, nutraceuticals, pharmaceuticals and dietary plans to keep you younger for a longer time.

There is no doubt that people in their sixties and even seventies today will live considerably longer and healthier lives. Thanks to technology advances and partially to Google, Blogspot, Facebook, Youtube and other communications mediums these lives will be much happier than the lives of our parents.

The governments worldwide are considering shifting the retirement age to late sixties or even past seventy for a good reason. There are over $8 billion spent annually on aging research and over 25% of this spending goes into dieting, neutraceuticals and exercise research and health education. That is over $2 billion!
Here we will share some fruits of this research and discuss ways to improve your diet to stay young longer and significantly increase your health span.